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The threshold shift paradigm of obesity: evidence from surgically induced weight loss

Its not just a number its an early warning sign from your body

Current research shows that stimulation through GLP-2/GLP-2R signaling involves activation of adenylyl cyclase, increased cAMP and PKA accumulation, and eventually ELK-1/c-fos/c-jun gene activation

While those taking semaglutide (Wegovy) and tirzepatide (Mounjaro) lost double the amount of weight compared with people using older jabs 16kg on average patients put on 9.6kg within a year, meaning they could expect to regain all 16kg again in just over 20 months

As a weight loss doctor, I often receive questions from patients about the different types of weight loss medications available and how they compare to each other