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Ethics declarations Ethics approval and consent to participate The ethics approval of the SUSTAIN CSX trial applies for this nested substudy

Choosing treatments that have been proven safe and effective through clinical research and FDA review helps ensure you are making informed decisions about your health

It's important to note that individual responses to TB-500 can vary, and additional research is necessary to establish its efficacy and safety in specific conditions

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Dysregulation of this pathway, leading to increased production of neurotoxic metabolites, is implicated in depression (Bansal et al., 2018)