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Some positive changes usually occur, such as reversal of side effects, especially nausea and constipation

While medications maintain sustained, supraphysiologic hormone levels and typically produce significant weight reduction and HbA1c decreases, food-stimulated GLP-1 is released in brief pulses after meals and rapidly degraded within minutes, resulting in smaller metabolic improvements

As a result, unresolved shame or self-critical schemas may continue to influence emotional functioning, body image, and interpersonal behavioreven in the context of metabolic improvement

Weeks 25-48: Maintenance Optimization Later treatment phases involve continued improvement at diminishing rates

As a result, Ozempic may lead to a buildup and release of hydrogen sulfide gas