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Although retatrutide has shown substantial weight-loss efficacy in adults with obesity, the relative contributions of reduced appetite, altered food reward, enhanced energy expenditure, and glucagon-related metabolic effects remain incompletely understood (109)

However, beyond weight gain, obesity involves a series of obesity-related diseases, which in patients with PWS can have a stronger impact, considering the early onset of obesity, the difficulties in adhering to lifestyle changes, use of psychotropic medications, and the inability to communicate some symptoms linked to mental retardation [24, 28]

Zinc offers anti-inflammatory properties to protect cells from oxidative damage

Consultation with specialists in reproductive endocrinology may be beneficial for those with complex fertility concerns

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