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Furthermore, recent studies have highlighted SFN's role in gut microbiota modulation

In this article, the authors showed that uPAR is expressed in senescence cells, both in in vivo and in vitro models (liver fibrosis, pancreatic intraepithelial neoplasia, senescent melanocytes, or lung cancer) correlated to a lack of expression in healthy tissue, except for the bronchial epithelium and a subset of immune cells in which a weak expression of uPAR was detected

The resulting data were indicative of the suppressive impact of TFR2 on the viability of TNBC cells by inducing ferroptosis

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Studies have shown that serum IL-6 levels are significantly elevated in patients with ALD and are directly linked to liver dysfunction and the severity of ALD complications [142, 143]