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The corresponding shared and unique structures (SUS) plot was generated to provide information on the contribution of AAs to the group discrimination

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Severe reactions linked to Lamictal include: Anticonvulsant hypersensitivity syndrome (AHS) : Characterized by rashes, fever, and potential organ involvement during or after using antiepileptic medications Stevens-Johnson syndrome (STS) : Involves skin peeling, blisters across the body (including the eyes), severe fluid loss, and mineral imbalances Toxic epidermal necrolysis (TEN) : Causes extensive skin peeling and blisters that affect more than 30% of the body Drug rash with eosinophilia and systemic symptoms (DRESS) : Includes a rash, lymphadenopathy (swollen lymph nodes), and eosinophilia In rare cases, Lamictal may trigger autoimmune conditions like lupus or other inflammatory disorders

doi: 10.3390/ijms23052717