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SS(NHS-CM) 2 was reacted with TPP-pentylamine or d 15 TPP-pentylamine generated in situ from their hydrobromide salts to give the desired symmetrical disulfides, SS(CAM-TPP) 2 and SS(CAM- d 15 TPP) 2 , respectively

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Despite the presence of L cells in the duodenum, they are not responsible for the GLP-1 release as removing the jejunum-ileum before infusing the duodenal compartment with fat prevents the observed increase of plasma GLP-1 (Roberge et al., 1996)