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It is recommended to consult with a doctor to discuss metabolic goals and to ensure that any treatments are safe, legal, and appropriate for your specific health needs

As clinical signs of cobalamin deficiency include chronic wasting or failure to thrive, malaise, and gastrointestinal signs such as diarrhea, serum cobalamin concentration should be measured in any dog with poor response to enzyme replacement therapy for EPI

Start with once-daily application and observe for any reaction before increasing to twice daily

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But how exactly do they work, and could they fit into your weight loss plan