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A growing number of evidence indicates that GLP-1-based therapies have anti-inflammatory effects in various cells, tissues, and organs by reducing the synthesis of pro-inflammatory cytokines and limiting immune cell infiltration

This process causes lactate accumulation and promotes the inflammatory behavior of immune cells (69, 70)

Circulation 150 , 12161218 (2024)

Here's what that looks like in practice

DOI: 10.1016/j.eclinm.2025.103363, Further Reading All Glucagon-like Peptide-1 Content Oral GLP-1 Pills for Weight Loss: How Orforglipron Works GLP-1 and Diet: Evidence-Based Strategies for Better Weight Loss Is Berberine Really Natures Ozempic