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J Anal Bioanal Chem
CHAC1 upregulation has been shown to be associated with the suppression of SLC7A11 and NRF2 and a surge in lipid peroxidation
Fumarate itself is a Michael acceptor, and the covalent attachment to protein cysteines corresponds to the post-translational modification known as succination [142] and fumarate has been recently demonstrated to yield a glutathione thioether in in vitro treated cells [142]
Anal Sci
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