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No functional or behavioral toxicity was observed in offspring of rats
Similarly, there was no efflux system for [Ser 8 ]GLP-1 to exit the brain other than following the reabsorption of cerebrospinal fluid (CSF)
The SELECT trial data showing 20% reduction in MACE makes semaglutide the only compound in this class with proven cardiovascular benefit
But retatrutide is tuned so the GLP-1 and GIP parts keep blood sugar in check while the glucagon part just adds the extra burn
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