Instead, GIP may counteract nausea and vomiting via direct modulation of the area postrema/NST emesis circuitry (169) and exert protective effects on unfavorable altered gut motility ( 5.4 GIP and GLP-1 effects on lipid and glucose metabolism in adipose tissue and liver Fat and liver are two organs that play key roles in lipid and glucose metabolism, working together in concert and complimentarily to maintain lipid and glucose homeostasis
References Wharton S, Lau DCW, Vallis M, Sharma AM, Biertho L, Campbell-Scherer D, et al
Why is the neurobiology of nausea and vomiting so important
This allows them to collect and analyse the substances (like fats and sugars) that the fat cells release and that may help cancer cells grow and spread
NICE guidance on suspected cancer recognition and referral (NG12) provides thresholds for urgent investigation of potential pancreatic cancer, including immediate referral for obstructive jaundice, and urgent direct-access CT scanning (within 2 weeks) for people aged 60 and over with weight loss and specific symptoms
