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doi: 10.1016/j.peptides.2019.170174 56 DupreJRossSAWatsonDBrownJC

Insulin sensitizers: For patients with insulin resistance, medications such as metformin can be prescribed to improve insulin sensitivity, leading to better glucose control

Denmark Research suggests they may support nerve repair, enhance cognitive function, and protect against neurodegenerative conditions, though more studies are needed to confirm their efficacy and safety for these purposes

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The challenge with retatrutide is that eating enough protein becomes physically difficult when appetite is suppressed