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Most GLP-1RAs, aside from a new oral formulation of semaglutide (Rybelsus tablets), are administered subcutaneously via pen-like devices (once daily to once weekly) due to poor oral bioavailability, and all are renally excreted 1

These drugs work by mimicking the GLP-1 hormone and binding to GLP-1 receptors in the brain and gut

Healing of the wounds is accomplished by resolution of vessel constriction, the primary platelet plug, the fibrin mesh which acts to stabilize the platelet plug, and resolution of the clot