glp-1 for ckd RAs, Other Agents, Underused in Patients Who Need Them the Most GLP1 Receptor Agonists vs SGLT2-I

Respiratory Depression: High doses can lead to respiratory paralysis

Ghanem N, Ha AN, Fakruzzaman M, Bang JI, Lee SC, Kong IK

Image Credit: zimmytws / Shutterstock A recent review article published in the Journal of Clinical Investigation summarized the adverse effects of glucagon-like peptide-1 receptor agonists (GLP-1RAs) and dual incretin receptor agonists such as tirzepatide

It plays a foundational role in physical development, tissue regeneration, and fat metabolismespecially during adolescence, sleep, and intense physical training

Its characterized by breathing disruptions during sleep caused by blocked airflow and increases the risk of heart and brain problems