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Triple Combination Therapy for Melasma Combination therapy using hydroquinone, tretinoin, and fluocinolone acetonide has demonstrated superior efficacy in treating melasma compared to monotherapy

Copper is essential for angiogenesis, nerve growth, and antioxidant defense

Moreover, according to Sarafian et al, prior studies have shown that chronic marijuana exposure causes a continual decline in GSH antioxidant systems and result in necrotic apoptosis [313], providing further evidence of THCs cytotoxic effects

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In one study, conducted with rats, glutathione was found to reduce the toxic effects of lead and cadmium. It can also bind with mercury, which causes various problems when accumulated in the body. Other studies suggest glutathione can help the body detoxify from persistent organic pollutants, which can build up in the body and cause damage. 3