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You develop signs of hypoglycaemia : Whilst both Rybelsus and Januvia have low intrinsic hypoglycaemia risk, combining them with insulin or sulphonylureas increases this possibility

When patients alternate between taking and missing doses, the gastrointestinal tract may not fully adapt to the medication

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Our study highlights GLP1Rs direct influence on hypertension-related genes in pathways such as adipocytokine signaling, fructose metabolism, CRP, and inflammation, alongside potential effects on calcium metabolism and mTOR activation