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A p-value 0.05 was considered statistically significant

Read review Dihexa for Autism Spectrum Disorder (ASD) The Campbell rs1858830 MET promoter C-allele autism finding (the strongest mechanistic anchor to Dihexa pharmacology), the January 2026 mGluR5 PET 16-23% lower availability, the December 2025 DAYBUE STIX (trofinetide) Rett approval, the March 2026 FDA leucovorin decision (CFD only, not autism), the 270,701 NHS open referrals breaching NICE NG142, and the ~700,000 UK autistic population

In September 2019 , the FDA approved Rybelsus , the first oral GLP-1 receptor agonist, available in 3 mg (starter dose), 7 mg, and 14 mg daily tablets

Findings suggested possible improvements in markers of kidney function and immunity, with researchers noting trends toward reduced progression of renal impairment in models

Side effects are comparable, though AOD 9604 has more clinical data supporting its safety profile