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demonstrated that KAT8 mediates the acetylation of YEATS4, antagonizing its interaction with the E3 ubiquitin ligase HUWE1 and subsequent ubiquitination and degradation, thus promoting bladder cancer progression [97]

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Most of the GSH (8085%) is stored in the cytosol, 1015% in the mitochondria (with an equal concentration between matrix and cytosol, thus requiring specific transport systems) and a small part in the endoplasmic reticulum (ER) (1, 6, 7)

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