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In summary, artesunate inhibits the activation of M1 macrophages and the RIPK1/RIPK3/MLKL signaling cascade by down-regulating Mincle expression, consequently reducing both the inflammatory response and necroptosis, thereby ameliorating renal injury in AKI

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Glutathione, which is present in every cell, is necessary to keep cells healthy and youthful-looking

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