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PMID 30835257

However, subsequent research has shown that carnitine acts to modulate thyroid hormones within our cells, so it can act like an agonist (a substance that initiates a response when combined with a receptor) helping thyroid hormone action in cases of hypothyroidism, and as an antagonist (blocker) in cases of hyperthyroidism

These may include obesity, type 2 diabetes, and a sedentary lifestyle

The researchers specifically noted this finding "could provide reassurance that a greater proportion of lean mass is not lost with retatrutide despite the overall increased weight loss." For a bodybuilder interpreting this data, the practical implication is clear