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Patients with MS have significantly lower serum UA than controls [156]
Hemoglobin A1c (HbA1c) is a crucial biomarker that reflects average blood glucose levels over the past two to three months
Common adverse effects include diarrhoea, abdominal cramping and nausea, particularly with magnesium oxide or citrate formulations
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286,287 Among the SCFAs, butyrate is the most potent HDAC inhibitor that is generally thought to inhibit the activity of class I HDACs (HDAC1, 2, 3, and 8) and class IIa HDACs (HDAC4, 5, 7, and 9), but not class IIb HDACs (HDAC6 and HDAC10) and class III HDACs (sirtuins)
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