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One study with more than 300 participants saw a 15.8% decrease in body weight for semaglutide after 68 weeks.3 Another study saw a 12.4% decrease after 72 weeks.4 Averaging those two outcomes, someone weighing 200 pounds could reasonably expect to lose around 14% of their body weight after about 16 months

The Latest Science About GLP-1 Drugs & Weight Loss Although GLP-1s aren't new (they've been used to treat diabetes for decades), new research continues to be published about them

No matter how GLP-1 nausea manifests, there are ways to manage this side effect

It focused on individual-level randomized clinical trial (RCT) data of GLP1-RA from the HARMONY program [Liraglutide (389 individuals) and Albiglutide (1,682 individuals)], the PRIBA study [Liraglutide (397 individuals), exenatide (223 individuals), and Tayside & Fife (415 individuals)

Patients who take Liraglutide see an 8-10% reduction in body weight on average