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Participants received weekly subcutaneous injections and maintained consistent plasma concentrations throughout the dosing period

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HepG2 cells showed an approximately 8% increase in survival after 48 h of exposure to C16-carnitine, whereas HT29 and HCT 116 cells exhibited reduced survival [67]

In addition, emerging therapies for NASH cirrhosis would have to demonstrate either reversal of fibrosis with associated reduction in portal hypertension or at least delay the progression with eventual decrease in liver-related outcomes