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For the cells to be able to survive in an anchorage-independent manner, they must possess anoikis resistance (121)

This is especially important if you are prone to developing peripheral neuropathy

Insulin resistance is a core problem with PCOS that is the cause of more than just weight gain

Therefore, complex I inhibition can exert both pro- and antiferroptotic effects: promoting ferroptosis via ubiquinol (CoQ 10 H 2 ) depletion, while simultaneously suppressing it through AMPK activation

Some doctors may approve low, supervised doses in specific cases, like high oxidative stress, but it's not something to self-prescribe