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It is a prescription medicine with a defined role in diabetes and obesity care, it can help with glycaemic control and weight reduction, but it can also cause nausea, vomiting, constipation and other gastrointestinal side effects

Additionally, GLP-1 has been shown to enhance the proliferation and differentiation of endothelial progenitor cells through upregulation of VEGF, potentially promoting angiogenesis that could contribute to retinal complications [101,102]

Up-regulation of genes involved in the insulin signalling pathway (IGF1, PTEN and IGFBP1) in the endometrium may link polycystic ovarian syndrome and endometrial cancer

Semaglutide is not approved for use during pregnancy or breastfeeding

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