[DOI] [PubMed] [Google Scholar] 185.Lemaire S.D., Michelet L., Zaffagnini M., Massot V., Issakidis-Bourguet E
When areas of the body are subject to ongoing inflammation, many issues can arise
Contaminants and reference standards Examine residual solvents, elemental impurities, water, microbial limits, and process-specific impurities
We have demonstrated the beneficial effect of G49, a dualAG, in resolving metabolic-dysfunction associated steatohepatitis (MASH) and improving liver regeneration under this pathological condition in C57BL/6J mice by targeting multiple homeostatic mechanisms including inflammation, oxidative/endoplasmic reticulum stress, mitochondrial dysfunction, and shifting glucose metabolism 13
142,143,144 In addition to MTL-CEBPA, MiNA Therapeutics has several saRNA candidates in preclinical development for undisclosed tumor types, metabolic diseases, and genetic disorders