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Using a flow cytometry-based assay for intracellular glutathione, we found that although melatonin increased cellular GSH levels, this effect was lost when cells were co-treated with melatonin and IKE ( Figure 6I )

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As GO enrichment scatterplot shown in Figure 3B, the most DEGs were distributed in the cytosolic large ribosomal subunit, cellular component, structural constituent of ribosome, obsolete oxidationreduction process, mitochondrion, biological process, translation, cytosolic small ribosomal subunit, oxidoreductase activity, molecular function, plasma membrane, extracellular region, nucleus, and zinc ion binding terms based on the gene number and enrichment factors

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