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Absorbance was recorded at 595 nm with a microplate reader (Tecan, Switzerland)

doi:10.1016/j.jddst.2022.103656 154

Mesenchymal stem cell therapy can reduce serum amylase and TNF- concentrations, increase serum IL-10 concentrations, reduce brain microvascular endothelial cell apoptosis, up-regulate claudin-5 levels, and reduce MMP-9 levels [57, 68]

Nrf2-dependent antioxidant pathway Allicin was also found to upregulate the expression of glutamate-cysteine ligase (GCL), the rate-limiting enzyme in glutathione synthesis, and other Phase II detoxifying/antioxidant enzymes, likely via the activation of the nuclear factor E2-related factor 2 (Nrf2)-dependent pathway (19)

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