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doi:10.1016/j.pneurobio.2014.11.004

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Current studies still commonly face limitations in causal inference and model systems: most findings are derived from in vitro induction systems or single animal models, making it difficult to simultaneously resolve the coordinated influence of tissue substrate availability, intercellular metabolic division of labor, and local cytokine networks on metabolic pathways

Rates of change of pons and middle cerebellar peduncle diameters are diagnostic of multiple system atrophy of the cerebellar type

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