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For example, orally administered Schisandra chinensis lignans must endure changes in pH and enzymatic activity as they pass through the GI system before reaching target sites such as colon cancer cells
Samples were concentrated to dryness in vacuum before dissolving in 150 L 80% methanol solution, then centrifuged again at 13 500 g and 4C for 10 min, and the supernatant was transferred to a new tube for LC-MS detection
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