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Description

10.1152/ajpgi.00223.2019 76

developed supramolecular prodrug nanoassemblies (SPNA) for reactive nitrogen species (RNS)-enhanced chemotherapy (Figure 3D) (Figures 3E, F), thereby generating highly toxic peroxynitrite anion (ONOO )

And its incredibly vulnerable during this transition

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This does not eliminate TMAO production entirely, as some circulating levocarnitine can be excreted into the gut, but it likely reduces the total TMAO burden compared to equivalent oral doses

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