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Unlocking melatonins anti-amyloidogenic potential AD is characterized by A aggregation, which in turn is associated with synaptic loss, oxidative stress, and mitochondrial dysfunction in the brain [32, 43,44,45,46,47]

Clinicians utilizing these findings have developed targeted treatment protocols, often referred to as the "Brewer Protocol," which focus on eradicating fungal colonization in the sinus cavities using biofilm disruptors and intranasal antifungals

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The ASIP gene helps regulate this system by influencing how strongly melanocortin receptors respond, which can affect the balance of darker, more UV-protective pigment and lighter pigment with less protection

95% CI 2.08 to 2.61