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Versions of this TBM are also found in other telomere-associated proteins that are recruited through similar domain:peptide interactions with TRF1 via the consensus motif F-X-L-X-P-X-(K/R) 3 , such as the telomerase inhibitor Pin2/TRF1-interacting protein (PinX1) 7,16 and the meiosis-specific telomere binder TERB1 17

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399 They can penetrate the cell membrane by themselves and effectively enhance the intracellular delivery of NADs, aiding their interaction with the target to achieve therapeutic goals