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Life-Threatening Respiratory Depression Serious, life-threatening, or fatal respiratory depression may occur with use of hydrocodone bitartrate and acetaminophen tablets, especially during initiation or following a dosage increase

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For severe allergic reactions (anaphylaxis): Emergency treatment includes: Intramuscular adrenaline (epinephrine) 500 micrograms (0.5ml of 1:1000) into the anterolateral thigh this is the first-line and most important treatment High-flow oxygen and airway management Intravenous fluids for circulatory support Antihistamines may be given for persistent skin symptoms but are not first-line treatment for anaphylaxis Hospital observation with duration based on risk assessment (minimum 2-6 hours for uncomplicated cases

Pulsed dye lasers (like the VBeam) take aim at blood vessels to fade redness