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Wegovy has been associated with modest increases in heart rate in clinical trials (typically 14 beats per minute on average, according to the SmPC)

2.2 Neurotoxic mechanisms METH induces neurotoxicity via a combination of oxidative stress, mitochondrial dysfunction, excitotoxicity, and neuroinflammation

The peptide is safe and well-tolerated, and it has been shown to improve sexual function in men with erectile dysfunction, diabetes, and spinal cord injury

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While these side effects often subside, they can discourage adherence to the treatment