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A 2016 study published in Nature Scientific Reports showed that GHK-Cu had no cytotoxicity to human keratinocytes at concentrations up to 5,800 micromolar over 72 hours and did not induce inflammatory biomarkers

The wide range reflects individual variation in requirements and the difficulty of over-dosing b12

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Translational Studies Combination research is more limited but exploratory studies have evaluated parallel administration to characterize additive effects on memory tasks, anxiety paradigms, and neurochemical markers

Note: A small human case series combining BPC-157 and TB-500 for joint injuries reported improved outcomes at higher combined doses (4 mg BPC + 6 mg TB-500 intra-articular) compared to lower doses [8]