In 2026, it remains the most evidence-backed carrier peptide in cosmetic science
Worth weighting on its own
In an open-label SUSTAIN 7 clinical trial published in the LANCET, 1,201 patients were randomly assigned to one of four treatment groups: semaglutide 0.5 mg (301 patients), dulaglutide 0.75 mg (299 patients), semaglutide 1.0 mg (300 patients), and dulaglutide 1.5 mg (299 patients)
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Here, we benchmarked several engineered laccase templates 22,23,24,25 , identified an ancestral fungal variant with slight activity in HEK293T cells and performed extensive directed evolution on the yeast surface to improve its activity (Fig