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Cell damage caused by free radicals is believed to play an important role in the progression of aging process and aging-related degenerative diseases (especially atherosclerosis, cataract, diabetes, neurodegenerative diseases, immunosystem disorders, and cancer formation)

Systemic : Inflammation regulation, damage repair, and inter-system communication (e.g., brain, gut, muscles, metabolism)

The accumulation of senescent cells contributes to cancer progression and increased resistance to treatment, emphasizing the need for new therapeutic strategies

Its implicated in many psychiatric disorders, most notably depression, and is the subject of many psychiatric medications