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Brainstem Activity Alters Diaphragm Circuit GLP-1 activity in brainstem centers may also alter the excitability of the diaphragm control circuit, thereby increasing the likelihood of brief spasms after meals or injections

Protocol Initiation: Treatment begins with conservative dosing that is gradually optimized based on symptom response and lab results

BPC-157's primary proposed mechanisms VEGF/angiogenesis and gastric/gut-lining signalling are directly relevant to both vascular and gastrointestinal research contexts

Data availability The study was approved by the Mass General Brigham Institutional Review Board

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