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found that aged rats treated with ALC showed improvement in NGF-binding capacity in brain regions, suggesting that certain forms of LC might enhance neuron responsiveness to neurotrophic factors in older rats [43]

Montgomery SA, Thal LJ, Amrein R

Beta-defensin 1, aryl hydrocarbon receptor and plasma kynurenine in major depressive disorder: metabolomics-informed genomics

All morning doses of the study treatments were taken with 120 mL of water after an overnight fast ( 6 h and with no fluid intake within the 2 h before dosing), followed by post-dose fasting for 30 min

Besides, it stimulated expression of early growth response 1 (egr-1) gene responsible for cytokine and growth factor generation and early extracellular matrix (collagen) formation (but also its repressor nerve growth factor 1-A binding protein-2 (nab2)) (44)