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Healthy individuals typically have Akkermansia making up 1 to 4 percent of their total gut bacteria

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[PubMed] [PMC] Garca-Monzn C, Martn-Prez E, Iacono OL, Fernndez-Bermejo M, Majano PL, Apolinario A, Larraaga E, Moreno-Otero R (2000) Characterization of pathogenic and prognostic factors of nonalcoholic steatohepatitis associated with obesity

Research indicates hepatic glutathione concentrations decline with age, oxidative stress, and certain genetic variations, potentially compromising liver detoxification capacity

Buijsse B, Lee DH, Steffen L, Erickson RR, Luepker RV, Jacobs DR Jr, Holtzman JL