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This could provide guidelines to help clinicians and individuals make informed decisions about long-term weight management

[DOI] [PMC free article] [PubMed] [Google Scholar] [98].Merry TL, Tran M, Stathopoulos M, Wiede F, Fam BC, Dodd GT, Clarke I, Watt MJ, Andrikopoulos S, Tiganis T, High-fat-fed obese glutathione peroxidase 1-deficient mice exhibit defective insulin secretion but protection from hepatic steatosis and liver damage

Alkylation base damage is converted into repairable double-strand breaks and complex intermediates in G2 cells lacking AP endonuclease

Some studies report mild side effects or adverse reactions

Obese mice treated with the compound for 28 days showed approximately a 30% reduction in body weight