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Those with uncontrolled diabetes, significant cardiovascular disease, or untreated sleep apnea: The drugs could make your conditions worse

Shoun H, Kim D-H, Uchiyama H, Sugiyama J

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This anticonvulsant activity is consistent with DSIPs proposed NMDA receptor modulation and adrenergic normalisation mechanisms, and establishes a neuroprotective research dimension distinct from its sleep biology