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The ratiometric readout of RT only responds to GSH (10 mM), but not to glycine (10 mM), cysteine (100 M) or a series of ROS/RNS (100 M)

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Despite their small size, they have immense biological significance in molecular biology: peptides function as a peptide hormone like PPY, enzymes, neurotransmitters, and signal molecules that mediate immune responses, cell signaling, tissue repair, and metabolic regulation

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