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STEP 1 demonstrated that semaglutide 2.4 mg weekly resulted in mean weight loss of 14.9% over 68 weeks, compared to 2.4% with placebo

Despite showing efficacy in ex vivo whole blood cultures, auranofin did not affect sputum culture conversion in early clinical trials [25]

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This comparison helps clarify how AOD 9604 is positioned relative to upstream GH-axis modulators in experimental systems

Semaglutide Dose and Weight Loss Results Clinical trials demonstrate a clear doseresponse relationship: patients on 2.4 mg semaglutide lose approximately 15% of body weight over 68 weeks, compared to roughly 6% weight loss in the 1.7 mg group and 3% in the 0.5 mg group