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Taking too much can induce severe dehydration, fainting, headaches or migraine

Although trunk fat, total fat, and total fat-free mass were all significantly decreased, no significant changes were observed in BMI or body weight in human studies[28]

The postload sampling test does burden biomedical protocols, however, this test was shortened to 2 hours in a recent study (Bostom et al, 1995b)

10.1210/er.2012-1055 94 McCulloughL

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