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Summary: Rybelsus causes nausea and sickness by slowing gastric emptying and acting on brain receptors that regulate appetite, creating sensations of fullness and queasiness that typically improve after 48 weeks

MPH and AAR were supported by the UK Medical Research Council (MR/N026101/1 and MR/T044853/1), Asociacin Niemann Pick de Fuenlabrada and Niemann-Pick UK

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