Due to safety regulations, a face-to-face medical review is required before dispensing
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Other (less serious) concerns are if EGF can properly penetrate the skin (as it is a medium-sized, polar molecule, so a special delivery system is probably needed), if it can affect collagen synthesis (or just works on the surface plumping up only the upmost layers of the skin) and if it has beneficial effects at all when used in isolation versus when used in a "conditioned media" that contains lots of growth factors resembling the synergistic balance found in the skin
That is why treatment for a confirmed deficiency often starts with a higher frequency, sometimes weekly, for a defined period
Start with a balanced diet that includes enough protein, soluble fiber, and healthy fats