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Even though the specific roles that NKCC2 in these organs may have in glucose homeostasis remain unexplored, the potential relevance of extrarenal NKCC2 is underlined by the following: i ) the gluconeogenic capacity (Watford, 2005) of the small intestine supplies circulating glucose (Penhoat et al., 2014) and prevents obesity-related hepatic steatosis (Vily-Petit et al., 2020), ii ) the hypothalamus plays a central role in endocrine integration of fuel homeostasis, control of water/energy intake and feeding behavior (Schwartz et al., 2000

doi: 10.1161/hypertensionaha.123.22649 72 McGarrahRWWhitePJ

F., Tao, H., Linton, E

However, some patients may experience hair loss, thinning, or shedding while taking these medications, and if so, Dr